The general mode of translation inhibition by macrolide antibiotics

Macrolides are clinically important antibiotics thought to inhibit bacterial growth by impeding the passage of newly synthesized polypeptides through the nascent peptide exit tunnel of the bacterial ribosome. Recent data challenged this view by showing that macrolide antibiotics can differentially a...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Kannan, Krishna, Kanabar, Pinal, Schryer, David, Florin, Tanja, Oh, Eugene, Bahroos, Neil, Tenson, Tanel, Weissman, Jonathan S., Mankin, Alexander S.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2014
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234590/
https://ncbi.nlm.nih.gov/pubmed/25349425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1417334111
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