Orally Bioavailable 6-Chloro-7-methoxy-4(1H)-quinolones Efficacious against Multiple Stages of Plasmodium

[Image: see text] The continued proliferation of malaria throughout temperate and tropical regions of the world has promoted a push for more efficacious treatments to combat the disease. Unfortunately, more recent remedies such as artemisinin combination therapies have been rendered less effective d...

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Publicado en:J Med Chem
Autores principales: Cross, R. Matthew, Flanigan, David L., Monastyrskyi, Andrii, LaCrue, Alexis N., Sáenz, Fabián E., Maignan, Jordany R., Mutka, Tina S., White, Karen L., Shackleford, David M., Bathurst, Ian, Fronczek, Frank R, Wojtas, Lukasz, Guida, Wayne C., Charman, Susan A., Burrows, Jeremy N., Kyle, Dennis E., Manetsch, Roman
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2014
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234439/
https://ncbi.nlm.nih.gov/pubmed/25148516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm500942v
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