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Metal-Free Arylation of Ethyl Acetoacetate with Hypervalent Diaryliodonium Salts: an Immediate Access to Diverse 3-Aryl-4(1H)-Quinolones

[Image: see text] A clean arylation protocol of ethyl acetoacetate was developed using hypervalent diaryliodonium salts under mild and metal-free conditions. The scope of the reaction, using symmetric and unsymmetric iodonium salts with varying sterics and electronics was examined. Further, this met...

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Detalhes bibliográficos
Publicado no:J Org Chem
Main Authors: Monastyrskyi, Andrii, Namelikonda, Niranjan K., Manetsch, Roman
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4479256/
https://ncbi.nlm.nih.gov/pubmed/25558982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo5023958
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