Orally Bioavailable 6-Chloro-7-methoxy-4(1H)-quinolones Efficacious against Multiple Stages of Plasmodium

[Image: see text] The continued proliferation of malaria throughout temperate and tropical regions of the world has promoted a push for more efficacious treatments to combat the disease. Unfortunately, more recent remedies such as artemisinin combination therapies have been rendered less effective d...

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Detalhes bibliográficos
Publicado no:J Med Chem
Main Authors: Cross, R. Matthew, Flanigan, David L., Monastyrskyi, Andrii, LaCrue, Alexis N., Sáenz, Fabián E., Maignan, Jordany R., Mutka, Tina S., White, Karen L., Shackleford, David M., Bathurst, Ian, Fronczek, Frank R, Wojtas, Lukasz, Guida, Wayne C., Charman, Susan A., Burrows, Jeremy N., Kyle, Dennis E., Manetsch, Roman
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234439/
https://ncbi.nlm.nih.gov/pubmed/25148516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm500942v
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