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Scrapie prions selectively modify the stress response in neuroblastoma cells.

The fundamental event underlying scrapie infection seems to be a conformational change in the prion protein. To investigate proteins that might feature in the conversion of the cellular prion protein (PrPC) into the scrapie isoform (PrPSc), we examined mouse neuroblastoma N2a cells for the expressio...

詳細記述

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書誌詳細
主要な著者: Tatzelt, J, Zuo, J, Voellmy, R, Scott, M, Hartl, U, Prusiner, S B, Welch, W J
フォーマット: Artigo
言語:Inglês
出版事項: 1995
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC42335/
https://ncbi.nlm.nih.gov/pubmed/7708753
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