Scrapie prions selectively modify the stress response in neuroblastoma cells.

The fundamental event underlying scrapie infection seems to be a conformational change in the prion protein. To investigate proteins that might feature in the conversion of the cellular prion protein (PrPC) into the scrapie isoform (PrPSc), we examined mouse neuroblastoma N2a cells for the expressio...

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Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Tatzelt, J, Zuo, J, Voellmy, R, Scott, M, Hartl, U, Prusiner, S B, Welch, W J
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1995
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42335/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7708753/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.7.2944
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