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Scrapie prions selectively modify the stress response in neuroblastoma cells.

The fundamental event underlying scrapie infection seems to be a conformational change in the prion protein. To investigate proteins that might feature in the conversion of the cellular prion protein (PrPC) into the scrapie isoform (PrPSc), we examined mouse neuroblastoma N2a cells for the expressio...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Tatzelt, J, Zuo, J, Voellmy, R, Scott, M, Hartl, U, Prusiner, S B, Welch, W J
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42335/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7708753/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.7.2944
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