Computational modeling of Takotsubo cardiomyopathy: effect of spatially varying β-adrenergic stimulation in the rat left ventricle

In Takotsubo cardiomyopathy, the left ventricle shows apical ballooning combined with basal hypercontractility. Both clinical observations in humans and recent experimental work on isolated rat ventricular myocytes suggest the dominant mechanisms of this syndrome are related to acute catecholamine o...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Land, Sander, Niederer, Steven A., Louch, William E., Røe, Åsmund T., Aronsen, Jan Magnus, Stuckey, Daniel J., Sikkel, Markus B., Tranter, Matthew H., Lyon, Alexander R., Harding, Sian E., Smith, Nicolas P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Integrative Cardiovascular Physiology and Pathophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233305/
https://ncbi.nlm.nih.gov/pubmed/25239804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00443.2014
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