Computational modeling of Takotsubo cardiomyopathy: effect of spatially varying β-adrenergic stimulation in the rat left ventricle

In Takotsubo cardiomyopathy, the left ventricle shows apical ballooning combined with basal hypercontractility. Both clinical observations in humans and recent experimental work on isolated rat ventricular myocytes suggest the dominant mechanisms of this syndrome are related to acute catecholamine o...

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Bibliografische gegevens
Gepubliceerd in:Am J Physiol Heart Circ Physiol
Hoofdauteurs: Land, Sander, Niederer, Steven A., Louch, William E., Røe, Åsmund T., Aronsen, Jan Magnus, Stuckey, Daniel J., Sikkel, Markus B., Tranter, Matthew H., Lyon, Alexander R., Harding, Sian E., Smith, Nicolas P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2014
Onderwerpen:
Integrative Cardiovascular Physiology and Pathophysiology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233305/
https://ncbi.nlm.nih.gov/pubmed/25239804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00443.2014
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