Computational modeling of Takotsubo cardiomyopathy: effect of spatially varying β-adrenergic stimulation in the rat left ventricle

In Takotsubo cardiomyopathy, the left ventricle shows apical ballooning combined with basal hypercontractility. Both clinical observations in humans and recent experimental work on isolated rat ventricular myocytes suggest the dominant mechanisms of this syndrome are related to acute catecholamine o...

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Dades bibliogràfiques
Publicat a:Am J Physiol Heart Circ Physiol
Autors principals: Land, Sander, Niederer, Steven A., Louch, William E., Røe, Åsmund T., Aronsen, Jan Magnus, Stuckey, Daniel J., Sikkel, Markus B., Tranter, Matthew H., Lyon, Alexander R., Harding, Sian E., Smith, Nicolas P.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2014
Matèries:
Integrative Cardiovascular Physiology and Pathophysiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233305/
https://ncbi.nlm.nih.gov/pubmed/25239804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00443.2014
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