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Epitope-specific regulation of memory programming by differential duration of antigen presentation to influenza-specific CD8+ T cells

Memory CD8(+) T cells are programmed during the primary response for robust secondary responsiveness. Here we show that CD8(+) T cells responding to different epitopes of influenza virus received qualitatively different signals during the primary response that altered their secondary responsiveness....

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Bibliografische gegevens
Gepubliceerd in:Immunity
Hoofdauteurs: Ballesteros-Tato, André, León, Beatriz, Lee, Byung O., Lund, Frances E., Randall, Troy D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233138/
https://ncbi.nlm.nih.gov/pubmed/25035957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2014.06.007
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