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CD40-deficient, Influenza-specific CD8 Memory T Cells Develop and Function Normally in a CD40-sufficient Environment

Two models have been proposed to explain the requirement for CD40 signaling in CD8 T cell responses. The first model suggests that CD4 T cells activate antigen-presenting cells (APCs) through CD40 signaling (APC licensing). In turn, licensed APCs are able to prime naive CD8 T cells. The second model...

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Detalhes bibliográficos
Main Authors: Lee, Byung O., Hartson, Louise, Randall, Troy D.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194135/
https://ncbi.nlm.nih.gov/pubmed/14657225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20031440
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