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Epitope-specific regulation of memory programming by differential duration of antigen presentation to influenza-specific CD8+ T cells
Memory CD8(+) T cells are programmed during the primary response for robust secondary responsiveness. Here we show that CD8(+) T cells responding to different epitopes of influenza virus received qualitatively different signals during the primary response that altered their secondary responsiveness....
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Publicado no: | Immunity |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4233138/ https://ncbi.nlm.nih.gov/pubmed/25035957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2014.06.007 |
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