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FoxP3(+) regulatory T cells promote influenza-specific Tfh responses by controlling IL-2 availability
Here we test the role of FoxP3(+) regulatory T cells (Tregs) in controlling T follicular helper (Tfh) and germinal-center (GC) B cell responses to influenza. In contrast to the idea that Tregs suppress T cell responses, we find that Treg depletion severely reduces the Tfh cell response to influenza...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4013682/ https://ncbi.nlm.nih.gov/pubmed/24633065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4495 |
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