Dynamic regulation of T Follicular Regulatory cell responses by interleukin 2 during influenza infection

Interleukin 2 (IL-2) promotes Foxp3(+)-regulatory T (T(reg)) cell responses, but inhibits T follicular helper (T(FH)) cell development. However, it is not clear how IL-2 affects T follicular regulatory (T(FR)) cells, a cell type with properties of both T(reg) and T(FH) cells. Using an influenza infe...

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Publicado no:Nat Immunol
Main Authors: Botta, Davide, Fuller, Michael J., Marquez-Lago, Tatiana T., Bachus, Holly, Bradley, John. E., Weinmann, Amy S., Zajac, Allan. J., Randall, Troy D., Lund, Frances E., León, Beatriz, Ballesteros-Tato, André
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679073/
https://ncbi.nlm.nih.gov/pubmed/28892471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3837
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