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Interleukin-2 inhibits germinal center formation by limiting T follicular helper differentiation
T follicular helper (Tfh) cells promote T-dependent humoral immune responses by providing T cell help to B cells and by promoting germinal center (GC) formation and long-lived antibody responses. However, the cellular and molecular mechanisms that control Tfh differentiation in vivo are incompletely...
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Hauptverfasser: | , , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
2012
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3361521/ https://ncbi.nlm.nih.gov/pubmed/22464171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.02.012 |
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