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Interleukin-2 inhibits germinal center formation by limiting T follicular helper differentiation

T follicular helper (Tfh) cells promote T-dependent humoral immune responses by providing T cell help to B cells and by promoting germinal center (GC) formation and long-lived antibody responses. However, the cellular and molecular mechanisms that control Tfh differentiation in vivo are incompletely...

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Détails bibliographiques
Auteurs principaux: Ballesteros-Tato, André, León, Beatriz, Graf, Beth A., Moquin, Amy, Adams, Pamela Scott, Lund, Frances E., Randall, Troy D.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361521/
https://ncbi.nlm.nih.gov/pubmed/22464171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.02.012
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