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Prolonged antigen presentation by immune complex–binding dendritic cells programs the proliferative capacity of memory CD8 T cells

The commitment of naive CD8 T cells to effector or memory cell fates can occur after a single day of antigenic stimulation even though virus-derived antigens (Ags) are still presented by DCs long after acute infection is resolved. However, the effects of extended Ag presentation on CD8 T cells are u...

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Bibliographic Details
Main Authors: León, Beatriz, Ballesteros-Tato, André, Randall, Troy D., Lund, Frances E.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4113940/
https://ncbi.nlm.nih.gov/pubmed/25002751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20131692
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