Down-regulation of Smad7 expression by ubiquitin-dependent degradation contributes to renal fibrosis in obstructive nephropathy in mice

Overexpression of transforming growth factor β (TGF-β) has been shown to play pathogenic roles in progression of renal fibrosis, and the severity of tubulointerstitial fibrosis correlates better with renal function than the severity of glomerulosclerosis. Smad proteins are signaling transducers down...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Fukasawa, Hirotaka, Yamamoto, Tatsuo, Togawa, Akashi, Ohashi, Naro, Fujigaki, Yoshihide, Oda, Toshiaki, Uchida, Chiharu, Kitagawa, Kyoko, Hattori, Takayuki, Suzuki, Sayuri, Kitagawa, Masatoshi, Hishida, Akira
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2004
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC423256/
https://ncbi.nlm.nih.gov/pubmed/15173588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400035101
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