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Ubiquitin-Dependent Degradation of Smad2 Is Increased in the Glomeruli of Rats with Anti-Thymocyte Serum Nephritis

The overexpression of transforming growth factor (TGF)-β and Smad-mediated intracellular TGF-β signaling in the kidney underlies the development of renal scarring from pathological matrix accumulation. However, changes in the Smad proteins during the progression of kidney disease are unclear. In thi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Togawa, Akashi, Yamamoto, Tatsuo, Suzuki, Hiroyuki, Fukasawa, Hirotaka, Ohashi, Naro, Fujigaki, Yoshihide, Kitagawa, Kyoko, Hattori, Takayuki, Kitagawa, Masatoshi, Hishida, Akira
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2003
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868293/
https://ncbi.nlm.nih.gov/pubmed/14507671
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