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Evaluation of sgRNA Target Sites for CRISPR-Mediated Repression of TP53

The CRISPR (clustered regularly interspaced short palindromic repeats) platform has been developed as a general method to direct proteins of interest to gene targets. While the native CRISPR system delivers a nuclease that cleaves and potentially mutates target genes, researchers have recently emplo...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Lawhorn, Ingrid E. B., Ferreira, Joshua P., Wang, Clifford L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232525/
https://ncbi.nlm.nih.gov/pubmed/25398078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113232
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