Hsp70 promotes TNF-mediated apoptosis by binding IKKγ and impairing NF-κB survival signaling

The major heat shock protein, Hsp70, can protect against cell death by directly interfering with mitochondrial apoptosis pathways. However, Hsp70 also sensitizes cells to certain apoptotic stimuli like TNF. Little is known about how Hsp70 enhances apoptosis. We demonstrate here that Hsp70 promotes T...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ran, Ruiqiong, Lu, Aigang, Zhang, Lu, Tang, Yang, Zhu, Hongyan, Xu, Huichun, Feng, Yuxin, Han, Chun, Zhou, Guoping, Rigby, Alan C., Sharp, Frank R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2004
Gaiak:
Research Papers
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC423196/
https://ncbi.nlm.nih.gov/pubmed/15198984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1188204
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak