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Effective sample size for computing prior hyperarameters in Bayesian phase I-II dose-finding
BACKGROUND: The efficacy-toxicity trade-off based design is a practical Bayesian phase I-II dose-finding methodology. Because the design's performance is very sensitive to prior hyperparameters and the shape of the target trade-off contour, specifying these two design elements properly is essen...
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| Pubblicato in: | Clin Trials |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4229398/ https://ncbi.nlm.nih.gov/pubmed/25179541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774514547397 |
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