טוען...
Parametric Dose Standardization for Optimizing Two-Agent Combinations in a Phase I–II Trial with Ordinal Outcomes
A Bayesian model and design are described for a phase I-II trial to jointly optimise the doses of a targeted agent and a chemotherapy agent for solid tumors. A challenge in designing the trial was that both the efficacy and toxicity outcomes were defined as four-level ordinal variables. To reflect p...
שמור ב:
| הוצא לאור ב: | J R Stat Soc Ser C Appl Stat |
|---|---|
| Main Authors: | , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2016
|
| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5328131/ https://ncbi.nlm.nih.gov/pubmed/28255183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/rssc.12162 |
| תגים: |
הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!
|