Llwytho...
Parametric Dose Standardization for Optimizing Two-Agent Combinations in a Phase I–II Trial with Ordinal Outcomes
A Bayesian model and design are described for a phase I-II trial to jointly optimise the doses of a targeted agent and a chemotherapy agent for solid tumors. A challenge in designing the trial was that both the efficacy and toxicity outcomes were defined as four-level ordinal variables. To reflect p...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | J R Stat Soc Ser C Appl Stat |
|---|---|
| Prif Awduron: | , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2016
|
| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5328131/ https://ncbi.nlm.nih.gov/pubmed/28255183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/rssc.12162 |
| Tagiau: |
Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
|