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CANDLES, an assay for monitoring GPCR induced cAMP generation in cell cultures
BACKGROUND: G protein-coupled receptors (GPCRs) represent a physiologically and pharmacologically important family of receptors that upon coupling to Gα(S) stimulate cAMP production catalyzed by adenylyl cyclase. Thus, developing assays to monitor cAMP production is crucial to screen for ligands in...
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| 出版年: | Cell Commun Signal |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4228090/ https://ncbi.nlm.nih.gov/pubmed/25366423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-014-0070-x |
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