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Survey of monoclonal antibody disposition in man utilizing a minimal physiologically-based pharmacokinetic model
Minimal physiologically based pharmacokinetic (mPBPK) models provide a simple and sensible approach that incorporates physiological elements into pharmacokinetic (PK) analysis when only plasma data are available. With this modeling concept, a second-generation mPBPK model was further developed with...
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| Publicado en: | J Pharmacokinet Pharmacodyn |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4226811/ https://ncbi.nlm.nih.gov/pubmed/25146360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-014-9374-0 |
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