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Second-generation minimal physiologically-based pharmacokinetic model for monoclonal antibodies
Minimal physiologically-based pharmacokinetic (mPBPK) models provide a sensible modeling approach when fitting only plasma (or blood) data yielding physiologically-relevant PK parameters that may provide more practical value than parameters of mammillary models. We propose a second-generation mPBPK...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3836053/ https://ncbi.nlm.nih.gov/pubmed/23996115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-013-9332-2 |
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