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Physiologically-based modeling of monoclonal antibody pharmacokinetics in drug discovery and development

Over the past few decades, monoclonal antibodies (mAbs) have become one of the most important and fastest growing classes of therapeutic molecules, with applications in a wide variety of disease areas. As such, understanding of the determinants of mAb pharmacokinetic (PK) processes (absorption, dist...

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Dades bibliogràfiques
Publicat a:Drug Metab Pharmacokinet
Autors principals: Glassman, Patrick M., Balthasar, Joseph P.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6378116/
https://ncbi.nlm.nih.gov/pubmed/30522890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dmpk.2018.11.002
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