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Hypercholesterolemia Inhibits Reendothelialization of Arterial Injuries by TRPC Channel Activation

OBJECTIVE: After arterial injury, endothelial cell (EC) migration is essential for healing, but lipid oxidation products activate TRPC6 and TRPC5 ion channels leading to increased intracellular calcium and inhibition of EC migration in vitro. The objective of this study was to further evaluate the r...

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Vydáno v:J Vasc Surg
Hlavní autoři: Rosenbaum, Michael A., Chaudhuri, Pinaki, Graham, Linda M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226809/
https://ncbi.nlm.nih.gov/pubmed/24820897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jvs.2014.04.033
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