Integration of TRPC6 and NADPH oxidase activation in lysophosphatidylcholine-induced TRPC5 externalization

Lipid oxidation products, including lysophosphatidylcholine (lysoPC), activate canonical transient receptor potential 6 (TRPC6) channels, and the subsequent increase in intracellular Ca(2+) leads to TRPC5 activation. The goal of this study is to elucidate the steps in the pathway between TRPC6 activ...

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Vydáno v:Am J Physiol Cell Physiol
Hlavní autoři: Chaudhuri, Pinaki, Rosenbaum, Michael A., Birnbaumer, Lutz, Graham, Linda M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2017
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5792165/
https://ncbi.nlm.nih.gov/pubmed/28835433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00028.2017
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