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Hypercholesterolemia Inhibits Reendothelialization of Arterial Injuries by TRPC Channel Activation

OBJECTIVE: After arterial injury, endothelial cell (EC) migration is essential for healing, but lipid oxidation products activate TRPC6 and TRPC5 ion channels leading to increased intracellular calcium and inhibition of EC migration in vitro. The objective of this study was to further evaluate the r...

詳細記述

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書誌詳細
出版年:J Vasc Surg
主要な著者: Rosenbaum, Michael A., Chaudhuri, Pinaki, Graham, Linda M.
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226809/
https://ncbi.nlm.nih.gov/pubmed/24820897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jvs.2014.04.033
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