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Hypercholesterolemia Inhibits Reendothelialization of Arterial Injuries by TRPC Channel Activation

OBJECTIVE: After arterial injury, endothelial cell (EC) migration is essential for healing, but lipid oxidation products activate TRPC6 and TRPC5 ion channels leading to increased intracellular calcium and inhibition of EC migration in vitro. The objective of this study was to further evaluate the r...

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Detalhes bibliográficos
Publicado no:J Vasc Surg
Main Authors: Rosenbaum, Michael A., Chaudhuri, Pinaki, Graham, Linda M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226809/
https://ncbi.nlm.nih.gov/pubmed/24820897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jvs.2014.04.033
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