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Inhibition of P110α and P110δ catalytic subunits of PI3 kinase reverses impaired arterial healing after injury in hypercholesterolemic male mice

Endothelial cell (EC) migration is critical for healing arterial injuries, such as those that occur with angioplasty. Impaired re-endothelialization following arterial injury contributes to vessel thrombogenicity, intimal hyperplasia, and restenosis. Oxidized lipid products, including lysophosphatid...

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書目詳細資料
發表在:Am J Physiol Cell Physiol
Main Authors: Chaudhuri, Pinaki, Smith, Andrew H., Graham, Linda M., Rosenbaum, Michael A.
格式: Artigo
語言:Inglês
出版: American Physiological Society 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8285636/
https://ncbi.nlm.nih.gov/pubmed/33689479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00600.2020
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