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Inhibition of P110α and P110δ catalytic subunits of PI3 kinase reverses impaired arterial healing after injury in hypercholesterolemic male mice

Endothelial cell (EC) migration is critical for healing arterial injuries, such as those that occur with angioplasty. Impaired re-endothelialization following arterial injury contributes to vessel thrombogenicity, intimal hyperplasia, and restenosis. Oxidized lipid products, including lysophosphatid...

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Vydáno v:Am J Physiol Cell Physiol
Hlavní autoři: Chaudhuri, Pinaki, Smith, Andrew H., Graham, Linda M., Rosenbaum, Michael A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8285636/
https://ncbi.nlm.nih.gov/pubmed/33689479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00600.2020
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