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Inhibition of P110α and P110δ catalytic subunits of PI3 kinase reverses impaired arterial healing after injury in hypercholesterolemic male mice

Endothelial cell (EC) migration is critical for healing arterial injuries, such as those that occur with angioplasty. Impaired re-endothelialization following arterial injury contributes to vessel thrombogenicity, intimal hyperplasia, and restenosis. Oxidized lipid products, including lysophosphatid...

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Detalhes bibliográficos
Publicado no:Am J Physiol Cell Physiol
Main Authors: Chaudhuri, Pinaki, Smith, Andrew H., Graham, Linda M., Rosenbaum, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8285636/
https://ncbi.nlm.nih.gov/pubmed/33689479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00600.2020
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