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Involvement of TNF-α Converting Enzyme in the Development of Psoriasis-Like Lesions in a Mouse Model
TNF-α plays a crucial role in psoriasis; therefore, TNF inhibition has become a gold standard for the treatment of psoriasis. TNF-α is processed from a membrane-bound form by TNF-α converting enzyme (TACE) to soluble form, which exerts a number of biological activities. EGF receptor (EGFR) ligands,...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4226544/ https://ncbi.nlm.nih.gov/pubmed/25384035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112408 |
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