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Key feature of the catalytic cycle of TNF-α converting enzyme involves communication between distal protein sites and the enzyme catalytic core

Despite their key roles in many normal and pathological processes, the molecular details by which zinc-dependent proteases hydrolyze their physiological substrates remain elusive. Advanced theoretical analyses have suggested reaction models for which there is limited and controversial experimental e...

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Opis bibliograficzny
Główni autorzy: Solomon, Ariel, Akabayov, Barak, Frenkel, Anatoly, Milla, Marcos E., Sagi, Irit
Format: Artigo
Język:Inglês
Wydane: National Academy of Sciences 2007
Hasła przedmiotowe:
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829242/
https://ncbi.nlm.nih.gov/pubmed/17360351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700066104
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