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Chaperone-like properties of the prodomain of TNFα-converting enzyme (TACE) and the functional role of its cysteine switch

The prodomain of TACE [TNFα (tumour necrosis factor α)-converting enzyme] is essential for the secretion of the functional enzyme. Previously, we showed that a TACE truncate was not secreted in the absence of the prodomain and that it was subjected to intracellular degradation. In the present study,...

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Bibliografski detalji
Glavni autori: Leonard, Jennifer D., Lin, Frank, Milla, Marcos E.
Format: Artigo
Jezik:Inglês
Izdano: Portland Press Ltd. 2005
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1135011/
https://ncbi.nlm.nih.gov/pubmed/15581423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041727
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