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Investigation of the Role of TNF-α Converting Enzyme (TACE) in the Inhibition of Cell Surface and Soluble TNF-α Production by Acute Ethanol Exposure

Toll-like receptors (TLRs) play a fundamental role in the immune system by detecting pathogen associated molecular patterns (PAMPs) to sense host infection. Ethanol at doses relevant for humans inhibits the pathogen induced cytokine response mediated through TLRs. The current study was designed to i...

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Detalhes bibliográficos
Main Authors: von Maltzan, Kristine, Tan, Wei, Pruett, Stephen B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272005/
https://ncbi.nlm.nih.gov/pubmed/22319556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029890
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