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PD-1 Impairs Secondary Effector Lung CD8(+) T Cells during Respiratory Virus Reinfection
Reinfections with respiratory viruses are common and cause significant clinical illness, yet precise mechanisms governing this susceptibility are ill defined. Lung Ag-specific CD8(+) T cells (T(CD8)) are impaired during acute viral lower respiratory infection by the inhibitory receptor PD-1. To dete...
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| Izdano u: | J Immunol |
|---|---|
| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2014
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4225166/ https://ncbi.nlm.nih.gov/pubmed/25339663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302208 |
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