A novel functional interplay between Progesterone Receptor-B and PTEN, via AKT, modulates autophagy in breast cancer cells

The tumour suppressor activity of the phosphatase and tensin homologue on chromosome 10 (PTEN) is subject of intense investigative efforts, although limited information on its regulation in breast cancer is available. Herein, we report that, in breast cancer cells, progesterone (OHPg), through its c...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: De Amicis, Francesca, Guido, Carmela, Santoro, Marta, Lanzino, Marilena, Panza, Salvatore, Avena, Paola, Panno, Maria Luisa, Perrotta, Ida, Aquila, Saveria, Andò, Sebastiano
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224558/
https://ncbi.nlm.nih.gov/pubmed/25216078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12363
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