Bergapten drives autophagy through the up-regulation of PTEN expression in breast cancer cells

BACKGROUND: Bergapten (5-methoxypsoralen), a natural psoralen derivative present in many fruits and vegetables, has shown antitumoral effects in a variety of cell types. In this study, it has been addressed how Bergapten in breast cancer cells induces autophagic process. RESULTS: In MCF7 and ZR-75 b...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: De Amicis, Francesca, Aquila, Saveria, Morelli, Catia, Guido, Carmela, Santoro, Marta, Perrotta, Ida, Mauro, Loredana, Giordano, Francesca, Nigro, Alessandra, Andò, Sebastiano, Panno, Maria L.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498523/
https://ncbi.nlm.nih.gov/pubmed/26148846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0403-4
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