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A novel functional interplay between Progesterone Receptor-B and PTEN, via AKT, modulates autophagy in breast cancer cells

The tumour suppressor activity of the phosphatase and tensin homologue on chromosome 10 (PTEN) is subject of intense investigative efforts, although limited information on its regulation in breast cancer is available. Herein, we report that, in breast cancer cells, progesterone (OHPg), through its c...

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Detaylı Bibliyografya
Yayımlandı:J Cell Mol Med
Asıl Yazarlar: De Amicis, Francesca, Guido, Carmela, Santoro, Marta, Lanzino, Marilena, Panza, Salvatore, Avena, Paola, Panno, Maria Luisa, Perrotta, Ida, Aquila, Saveria, Andò, Sebastiano
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BlackWell Publishing Ltd 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224558/
https://ncbi.nlm.nih.gov/pubmed/25216078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12363
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