載入...
Linear mtDNA fragments and unusual mtDNA rearrangements associated with pathological deficiency of MGME1 exonuclease
MGME1, also known as Ddk1 or C20orf72, is a mitochondrial exonuclease found to be involved in the processing of mitochondrial DNA (mtDNA) during replication. Here, we present detailed insights on the role of MGME1 in mtDNA maintenance. Upon loss of MGME1, elongated 7S DNA species accumulate owing to...
Na minha lista:
| 發表在: | Hum Mol Genet |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2014
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4222359/ https://ncbi.nlm.nih.gov/pubmed/24986917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu336 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|