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Is There Still Any Role for Oxidative Stress in Mitochondrial DNA-Dependent Aging?
Recent deep sequencing data has provided compelling evidence that the spectrum of somatic point mutations in mitochondrial DNA (mtDNA) in aging tissues lacks G > T transversion mutations. This fact cannot, however, be used as an argument for the missing contribution of reactive oxygen species (RO...
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| Publicado no: | Genes (Basel) |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5924517/ https://ncbi.nlm.nih.gov/pubmed/29561808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes9040175 |
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