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Inheritance of Mitochondrial DNA Recombinants in Double-Heteroplasmic Families: Potential Implications for Phylogenetic Analysis

Recently, somatic recombination of human mitochondrial DNA (mtDNA) was discovered in skeletal muscle. To determine whether recombinant mtDNA molecules can be transmitted through the germ line, we investigated two families, each harboring two inherited heteroplasmic mtDNA mutations. Using allele-spec...

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Main Authors: Zsurka, Gábor , Hampel, Kevin G. , Kudina, Tatiana , Kornblum, Cornelia , Kraytsberg, Yevgenia , Elger, Christian E. , Khrapko, Konstantin , Kunz, Wolfram S. 
格式: Artigo
語言:Inglês
出版: The American Society of Human Genetics 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1785346/
https://ncbi.nlm.nih.gov/pubmed/17236134
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