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Repeats, longevity and the sources of mtDNA deletions: evidence from “deletional spectra”
Perfect direct repeats and, in particular, the prominent 13-bp repeat, are thought to cause mitochondrial DNA (mtDNA) deletions, which have been associated with the aging process. Accordingly, individuals lacking the 13-bp repeat are highly prevalent among centenarians and the number of repeats nega...
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| Hoofdauteurs: | , , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2010
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2915442/ https://ncbi.nlm.nih.gov/pubmed/20591530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2010.05.006 |
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