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When man got his mtDNA deletions?

Somatic mtDNA mutations and deletions in particular are known to clonally expand within cells, eventually reaching detrimental intracellular concentrations. The possibility that clonal expansion is a slow process taking a lifetime had prompted an idea that founder mutations of mutant clones that cau...

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Publicat a:Aging Cell
Autors principals: Popadin, Konstantin, Safdar, Adeel, Kraytsberg, Yevgenya, Khrapko, Konstantin
Format: Artigo
Idioma:Inglês
Publicat: BlackWell Publishing Ltd 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326951/
https://ncbi.nlm.nih.gov/pubmed/24894296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12231
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