A carregar...
MGME1 processes flaps into ligatable nicks in concert with DNA polymerase γ during mtDNA replication
Recently, MGME1 was identified as a mitochondrial DNA nuclease with preference for single-stranded DNA (ssDNA) substrates. Loss-of-function mutations in patients lead to mitochondrial disease with DNA depletion, deletions, duplications and rearrangements. Here, we assess the biochemical role of MGME...
Na minha lista:
| Publicado no: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4937333/ https://ncbi.nlm.nih.gov/pubmed/27220468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw468 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|