POLRMT regulates the switch between replication primer formation and gene expression of mammalian mtDNA

Mitochondria are vital in providing cellular energy via their oxidative phosphorylation system, which requires the coordinated expression of genes encoded by both the nuclear and mitochondrial genomes (mtDNA). Transcription of the circular mammalian mtDNA depends on a single mitochondrial RNA polyme...

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Publicado en:Sci Adv
Autores principales: Kühl, Inge, Miranda, Maria, Posse, Viktor, Milenkovic, Dusanka, Mourier, Arnaud, Siira, Stefan J., Bonekamp, Nina A., Neumann, Ulla, Filipovska, Aleksandra, Polosa, Paola Loguercio, Gustafsson, Claes M., Larsson, Nils-Göran
Formato: Artigo
Lenguaje:Inglês
Publicado: American Association for the Advancement of Science 2016
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4975551/
https://ncbi.nlm.nih.gov/pubmed/27532055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1600963
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