POLRMT regulates the switch between replication primer formation and gene expression of mammalian mtDNA

Mitochondria are vital in providing cellular energy via their oxidative phosphorylation system, which requires the coordinated expression of genes encoded by both the nuclear and mitochondrial genomes (mtDNA). Transcription of the circular mammalian mtDNA depends on a single mitochondrial RNA polyme...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Kühl, Inge, Miranda, Maria, Posse, Viktor, Milenkovic, Dusanka, Mourier, Arnaud, Siira, Stefan J., Bonekamp, Nina A., Neumann, Ulla, Filipovska, Aleksandra, Polosa, Paola Loguercio, Gustafsson, Claes M., Larsson, Nils-Göran
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4975551/
https://ncbi.nlm.nih.gov/pubmed/27532055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1600963
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