Exosomes neutralize synaptic-plasticity-disrupting activity of Aβ assemblies in vivo

BACKGROUND: Exosomes, small extracellular vesicles of endosomal origin, have been suggested to be involved in both the metabolism and aggregation of Alzheimer’s disease (AD)-associated amyloid β-protein (Aβ). Despite their ubiquitous presence and the inclusion of components which can potentially int...

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Detalhes bibliográficos
Publicado no:Mol Brain
Main Authors: An, Kyongman, Klyubin, Igor, Kim, Youngkyu, Jung, Jung Hoon, Mably, Alexandra J, O’Dowd, Sean T, Lynch, Timothy, Kanmert, Daniel, Lemere, Cynthia A, Finan, Gina M, Park, Joon Won, Kim, Tae-Wan, Walsh, Dominic M, Rowan, Michael J, Kim, Joung-Hun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222117/
https://ncbi.nlm.nih.gov/pubmed/24284042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-6-47
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