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Temperature-Sensitive Mutants of Influenza A Virus: Evaluation of A/Victoria/3/75-ts-1[E] Recombinant Viruses in Volunteers

The Hong Kong/68-ts-1[E] virus and its Udorn/72 and Georgia/74 recombinants, which have a 38°C shutoff temperature and a ts lesion(s) on the genes coding for the P3 and NP proteins, were adequately attenuated and immunogenic in adult volunteers who lacked serum hemagglutination-inhibiting antibody (...

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Kaydedildi:
Yayımlandı:Infect Immun
Asıl Yazarlar: Murphy, Brian R., Markoff, Lewis J., Hosier, Nanette T., Rusten, Harold M., Chanock, Robert M., Kendal, Alan P., Douglas, R. Gordon, Betts, Robert F., Cate, Thomas R., Couch, Robert B., Levine, Myron M., Waterman, Daniel H., Holley, H. Preston
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 1978
Konular:
Viral Infections
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC421911/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/669819/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.20.3.671-677.1978
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