Temperature-sensitive mutants of influenza A virus: evaluation of the A/Victoria/75-ts-1A2 temperature-sensitive recombinant virus in seronegative adult volunteers.

An influenza A virus recombinant bearing the surface antigens of the A/Victoria/3/75 (H3N2) strain and the two ts genes of the A/Udorn/72-ts-1A2 virus was evaluated for attenuation, antigenicity, and protective effect in 42 doubly seronegative adult volunteers (i.e., individuals who lacked detectabl...

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Main Authors: Murphy, B R, Chanock, R M, Levine, M M, van Blerk, G A, Berquist, E J, Douglas, R G, Betts, R F, Couch, R B, Cate, T R
Format: Artigo
Sprog:Inglês
Udgivet: 1979
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC414156/
https://ncbi.nlm.nih.gov/pubmed/422239
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