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Temperature-sensitive mutants of influenza A virus: evaluation of the A/Victoria/75-ts-1A2 temperature-sensitive recombinant virus in seronegative adult volunteers.

An influenza A virus recombinant bearing the surface antigens of the A/Victoria/3/75 (H3N2) strain and the two ts genes of the A/Udorn/72-ts-1A2 virus was evaluated for attenuation, antigenicity, and protective effect in 42 doubly seronegative adult volunteers (i.e., individuals who lacked detectabl...

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Vydáno v:Infect Immun
Hlavní autoři: Murphy, B R, Chanock, R M, Levine, M M, van Blerk, G A, Berquist, E J, Douglas, R G, Betts, R F, Couch, R B, Cate, T R
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1979
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC414156/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/422239/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.23.2.249-252.1979
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